Magnesium 375^® Osteo

Magnesium is a mineral that is present in abundance in the human body, where it performs several essential functions.

In addition to being a necessary cofactor for the action of many enzymes, magnesium seems destined to play an increasingly important role in the prevention of many health disorders.

Magnesium works with calcium to maintain healthy bones and support mood stability, especially during stressful periods, and promotes the sleep cycle.

Manganese is a micronutrient present in small amounts in the human body, where it is mainly stored in the bones, liver, kidneys and pancreas.

Manganese has a protective effect on bones, cartilage and joints. In fact, this micronutrient is required for the synthesis of glycoproteins and proteoglycans that are necessary for the formation of connective tissue, and a deficiency is considered the cause of abnormal development of the skeleton in many animal species.

Vitamin D, present in some foods and made by our body through the action of sunlight, is an essential nutrient for human health.

Mainly known for the part it plays in calcium absorption and bone mineralization, vitamin D’s status also influences normal immune functions, cardiovascular health and neurocognitive activity, as shown by recent scientific evidence.

Vitamin D deficiency is an important risk factor for developing osteoporosis and adequate levels are associated with an increase in bone mineral density.

People at risk of deficiency are those who spend a lot of time at home, dress to cover the skin, and dark-skinned people. Even using protective sunscreens, which are very useful in reducing the risk of skin cancers, blocks the synthesis of this important vitamin.

Zinc is a trace element involved in the formation of many enzymes that catalyze important reactions in our body. Zinc is especially found in bones, skin, the prostate gland and eye tissue. Since there are no reserves of zinc in the body, a deficiency of it can rapidly manifest when there is inadequate intake.

Zinc deficiency is often observed in people over fifty years old and can contribute to oxidative inflammatory aging and to immunosenescence.

Vitamin K2, or menaquinone-7 (MK-7), the form with the best bioavailability, is redistributed through the blood to extrahepatic tissues like bones and blood vessels; this explains its increased involvement in osteogenesis and bone mineralization processes and the cell metabolism of vessel walls, as shown by growing scientific evidence.

Scientific evidence shows how MK-7 works in close synergy with vitamin D3 on bone differentiation and on the deposition of osteocalcin in the extracellular matrix. Osteocalcin is a protein produced by the osteoblasts during bone formation and its activation confers the ability to bind calcium.